- Victor Anichebe started for Sunderland and played full time as they beat Leicester 2 – 1 at home at the Stadium of Light. He was man of the match.
- Victor Moses started for Chelsea and played full time as they beat Manchester City 3 – 1 away at the Etihad Stadium.
- Kelechi Iheanacho came on for Manchester City in the 78th minute when he replaced John Stones. They lost 1 – 3 to Chelsea at home at the Etihad Stadium.
- Alex Iwobi came on for Arsenal in the 88th minute when he replaced Mesut Ozil. They beat West Ham 5 – 1 away at the London Stadium.
- Ahmed Musa came on for Leicester in the 73rd minute when he replaced Riyad Mahrez. They lost 2 – 1 away to Sunderland at the Stadium of Light.
- Odion Ighalo came on for Watford in the 77th minute when he replaced Zuniga. They lost 1 – 3 away to West Brom at The Hawthorns.
- Isaac Success was an unused substitute for Watford as they lost 1 – 3 away to West Brom at The Hawthorns.
- Mikel Obi was not selected for Chelsea’s game against Manchester City. Chelsea won 3 -1 away at the Etihad Stadium.